The board is laid out pretty well, my only gripe with the layout is the 4 pin ATX 12V header, I would still like to see this on an outside edge, it just makes wire management so much easier. There is also a 4 pin plug for a standard Molex right above the 1st PCI-E 1x connection, this also would have been nice to see either on the top edge or the right edge along with the rest of the connections. This Molex connection also forces the expansion slots down lower on the board. You might want to take this into consideration, especially if running in SLI. I would have had to relocate my pump if I was running dual video cards, as it is with a single card there is barely room for the pump.
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Review:
Viperlair