The title of this article looks a bit odd. Ron Gilbert isn't best known for his connection with Hothead. He's famous for creating Maniac Mansion and the Monkey Island series. But "Ron Gilbert, You Know, He Did Maniac Mansion and the Monkey Island Series" would mess up the homepage, so here we are.
Besides, the title is accurate. Gilbert is currently creative director at Hothead Games. He's working on two projects, the first of which is being shown to us at GDC with Gilbert in attendance. It's called Penny Arcade Adventures: On the Rain-Slick Precipice of Darkness, and it's based around characters from the Penny Arcade Internet comic strip created by Mike Krauhulik and Jerry Holkins - a.k.a. Gabe and Tycho.
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Source: Eurogamer